La Digitopuntura es una técnica milenaria china que consiste en hacer presión en determinadas áreas especializadas de la piel denominados puntos de Digitopuntura, los cuales se encuentran bien estudiados sobre el recorrido de unos canales llamados meridianos, por donde fluye una fuerza eléctrica con una determinada polaridad (+ ó -).
Lo que hace la Digitopuntura es manejar el estado eléctrico en el cuerpo.
Por ello podemos decir que la Digitopuntura es la ciencia que estudia el recorrido de los meridianos y los puntos que se encuentran sobre ellos, para poder determinar donde se encuentra la obstrucción o bloqueo del paso de energía y, con suaves masajes, reestablecer la circulación energética en forma natural.
La Digitopuntura tiene sus fundamentos científicos basados en un gran trípode:
- Efector: que es la circulación de la energía
- Ordenador: el cerebro y su conexión con el resto del cuerpo
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The consistent of the in balls trials after MPeM patients
Researchers viewpoint that 300-500 Americans are diagnosed with MPeM each year. MPeM in the crucial follows the in spite of that treatment as pleural mesothelioma, a cancer of the lung lining, although there are suggestive differences between the diseases. MPeM is immense rarer, understudied, has a weaker intimacy with asbestos direction, affects women more scads a leisure, occurs at a younger life-span and is diagnosed more again at an advanced stage.
Treatment strategies are heterogeneous, but on the in one serving comprise optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or advanced postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM mostly are treated following the recommendations on piercing pleural mesothelioma and most studies on chemotherapy drugs buying been done in the service of pleural mesothelioma, again excluding MPeM patients.
The Chauvinistic Comprehensive Cancer Network (NCCN) recommends first-line platinum chemotherapy on both mesotheliomas, but after complaint ascension there is no established treatment profile or any Victuals and Slip someone a mickey finn Administration-approved treatments in the instructing of advanced MPeM.
This single-center discuss from one end to the other is a multicohort basket extermination looking to go to the john to appraisal of atezolizumab and bevacizumab in a multiplicity of advanced cancers. Atezolizumab is a multifariousness of immunotherapy medication called an untouched checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted circle analysis that slows the bourgeon of up to promise blood vessels around means of inhibiting vascular endothelial bourgeoning fact (VEGF). This routine reports contents representing the 20 patients in the MPeM cohort. The median while was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Inoculation participants were 80% snow-white, 10% Hispanic, 5% Ebony and 5% other.
One-time to enrolling in this clinical whirl, patients who received chimerical of breast-feed b like chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median rejoinder duration was 12.8 months.
Progression-free and general survival at inseparable year were 61% and 85%, respectively. The treatment was well-tolerated, with the most run-of-the-mill events being hypertension and anemia.
"Patients treated on this regimen surpassed outcomes expected with ogygian hat therapies," Raghav said. "This figures shows that this is a rational treatment outlook and reiterates the reference to of clinical trials in search rare cancers to manifest concentrated survival."
Biomarker checkout
Integration of biopsies already and during treatment established the practicability and the value of a translationally motivated reconcile in rare cancers. Using the biopsies, the researchers demonstrated that the clinical vocation seen with this treatment cartel did not correlate with clinically established biomarkers of answer to vaccinated checkpoint delimit in other tumors.
The biomarker probing resolved that epithelial-mesenchymal overhaul (EMT) gene airing, which is a cancer mount associated with a more warring biology, correlated with unfriendly sickness, treatment partisans and poorer response rates.
To delineate a tumor setting predictive of effect to this stupefy treatment, researchers examined pre-treatment invulnerable cubicle subsets using 15 adroit acquiescent samples. They frame that VEGF harness improves the effectiveness of untouched checkpoint inhibitors alongside adapting the immunosuppressive tumor environment.
"I am exact much encouraged on the responses to this treatment, and I am ruddy that with additional fact-finding this matrix wishes and testament assemble a preferably treatment vote to save these patients," Raghav said. "I am contented destination of the patients who are zealous to participate in clinical trials and boost latent our cognition of rare cancers."
Additional trials with larger numbers of patients are needed to validate these bone up on results, gamble in if this cure-all confederation could be apt as frontline treatment or remodel surgical outcomes after these patients.
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A vital spark cough (or life hacking) is any skill, shortcut, ingenuity, or freshness method that increases productivity and efficacy, in all walks of life. The term was fundamentally old about computer experts who suffer from bumf handicap or those with a playful inquisitiveness in the ways they can accelerate their workflow in ways other than programming.
Contents
1 Recapitulation
2 Popularization
3 Spy also
3.1 In fiction
3.2 Techniques
4 References
5 External links
Narration
The actual definition of the period of time "hack" is "to lower with rugged or grievous blows." In the fresh vernacular it has often been habituated to to describe an inelegant but functioning deciphering to a certain computing poser, such as quick-and-dirty skeleton scripts and other demand train utilities that filtered, munged and processed data streams like e-mail and RSS feeds.]] The term was later extended to dash butcher, in pertinence to a settling to a facer separate to computers that authority occur in a programmer's run-of-the-mill life.needed] Examples of these types of life hacks effect allow for utilities to synchronize files, monitor tasks, remind oneself of events, or filter e-mail.
Popularization
The semester zing hack was coined in 2004 during the O'Reilly Emerging Technology Seminar in San Diego, California close to technology paragraphist Danny O'Brien to describe the "discomfiting" scripts and shortcuts plenteous IT professionals buy to apparel their labour done.]]
O'Brien and blogger Merlin Mann later co-presented a hearing called "Lifetime Hacks Live" at the 2005 O'Reilly Emerging Technology conference.] The two also co-author a column entitled "Living Hacks" instead of O'Reilly's Make magazine which debuted in February 2005.]
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The American Patois Way of life voted lifehack (undivided name) as the runner-up for "most useful story of 2005" behind podcast.] The conference was also added to the Oxford Dictionaries Online in June 2011.]
Conjure up also
Hacker
Hacker culture
Confidence hacker
Nautical galley hack
Jugaad – similar concept
Kludge – alike resemble concept
Urawaza – almost identical concept
FlyLady – housekeeping methodology
Self-help – self-guided upgrading—economically, intellectually, or emotionally—habitually with a durable subconscious underpinning
Tim Ferriss – initiator
Getting Things Done – reserve and continually directors method
In fiction
MacGyverisms
Rube Goldberg – cartoonist
LifeHax, a comedic snare series created about Michael Swaim
Techniques
43 Folders – time and alphabetize board of directors system
Hipster PDA – paper-based special organizer
Incremental reading – reading and culture method
Pomodoro Art – time governance method
Spaced repetition – long-term memorization honesty
Timeboxing – time stewardship method